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Activating SIRT-1 Signalling with the Mitochondrial-CoQ10 Activator Solanesol Improves Neurobehavioral and Neurochemical Defects in Ouabain-Induced Experimental Model of Bipolar Disorder

Bipolar disorder (BD) is a chronic mental illness characterized by mood fluctuations that range from depressive lows to manic highs. Several studies have linked the downregulation of SIRT-1 (silent mating type information regulation-2 homologs) signaling to the onset of BD and other neurological dys...

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Detalles Bibliográficos
Autores principales: Rajkhowa, Bidisha, Mehan, Sidharth, Sethi, Pranshul, Prajapati, Aradhana, Suri, Manisha, Kumar, Sumit, Bhalla, Sonalika, Narula, Acharan S., Alshammari, Abdulrahman, Alharbi, Metab, Alkahtani, Nora, Alghamdi, Saeed, Kalfin, Reni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415079/
https://www.ncbi.nlm.nih.gov/pubmed/36015107
http://dx.doi.org/10.3390/ph15080959