THE WNK4/SPAK PATHWAY STIMULATES ALVEOLAR FLUID CLEARANCE BY UPREGULATION OF EPITHELIAL SODIUM CHANNEL IN MICE WITH LIPOPOLYSACCHARIDE-INDUCED ACUTE RESPIRATORY DISTRESS SYNDROME

With-No lysine Kinases (WNKs) have been newly implicated in alveolar fluid clearance (AFC). Epithelial sodium channels (ENaCs) serve a vital role in AFC. The potential protective effect of WNK4 in acute respiratory distress syndrome (ARDS), mediated by ENaC-associated AFC was investigated in the stu...

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Detalles Bibliográficos
Autores principales: Deng, Wang, Qi, Di, Tang, Xu-Mao, Deng, Xin-Yu, He, Jing, Wang, Dao-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Basic Science Aspects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415224/
https://www.ncbi.nlm.nih.gov/pubmed/35670456
http://dx.doi.org/10.1097/SHK.0000000000001945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415224/
https://www.ncbi.nlm.nih.gov/pubmed/35670456
http://dx.doi.org/10.1097/SHK.0000000000001945

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