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Mismatch Repair Screening of Gastrointestinal Cancers: The Impact on Lynch Syndrome Detection and Immunotherapy

INTRODUCTION: Mismatch repair immunohistochemistry (MMR IHC) or microsatellite instability (MSI) testing is now routinely performed in patients with colorectal cancer (CRC) to select those requiring Lynch syndrome testing. MMR IHC is also carried out on CRC and upper gastrointestinal (GI) cancers to...

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Detalles Bibliográficos
Autores principales: R., Openshaw M., J., Williams, T., Foo, C., Moss, A., Wotherspoon, N., Starling., Z., Kemp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415243/
https://www.ncbi.nlm.nih.gov/pubmed/36018445
http://dx.doi.org/10.1007/s12029-022-00859-3