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Legionella pneumophila Infection of Human Macrophages Retains Golgi Structure but Reduces O-Glycans

Legionella pneumophila is an accidental pathogen that replicates intracellularly within the Legionella-containing vacuole (LCV) in macrophages. Within an hour of infection, L. pneumophila secretes effectors to manipulate Rab1 and intercept ER-derived vesicles to the LCV. The downstream consequences...

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Detalles Bibliográficos
Autores principales: Fu, Yanlin, Macwan, Vinitha, Heineman, Rebecca Emily-Sue, Terebiznik, Mauricio R., Harrison, Rene E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415278/
https://www.ncbi.nlm.nih.gov/pubmed/36015029
http://dx.doi.org/10.3390/pathogens11080908