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Inhibition of Hepatitis E Virus Replication by Novel Inhibitor Targeting Methyltransferase

Hepatitis E Virus (HEV) is a quasi-enveloped virus having a single-stranded, positive-sense RNA genome (~7.2 kb), flanked with a 5′ methylated cap and a 3′ polyadenylated tail. The HEV open reading frame 1 (ORF1) encodes a 186-kDa polyprotein speculated to get processed and produce Methyltransferase...

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Detalles Bibliográficos
Autores principales: Hooda, Preeti, Chaudhary, Meenakshi, Parvez, Mohammad K., Sinha, Neha, Sehgal, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415367/
https://www.ncbi.nlm.nih.gov/pubmed/36016400
http://dx.doi.org/10.3390/v14081778