Cargando…

Inhibition of Hepatitis E Virus Replication by Novel Inhibitor Targeting Methyltransferase

Hepatitis E Virus (HEV) is a quasi-enveloped virus having a single-stranded, positive-sense RNA genome (~7.2 kb), flanked with a 5′ methylated cap and a 3′ polyadenylated tail. The HEV open reading frame 1 (ORF1) encodes a 186-kDa polyprotein speculated to get processed and produce Methyltransferase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hooda, Preeti, Chaudhary, Meenakshi, Parvez, Mohammad K., Sinha, Neha, Sehgal, Deepak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415367/ https://www.ncbi.nlm.nih.gov/pubmed/36016400 http://dx.doi.org/10.3390/v14081778

Ejemplares similares

Inhibition of HEV Replication by FDA-Approved RdRp Inhibitors
por: Hooda, Preeti, et al.
Publicado: (2023)

Development of BacMam Induced Hepatitis E Virus Replication Model in Hepatoma Cells to Study the Polyprotein Processing
por: Kumar, Manjeet, et al.
Publicado: (2020)

Biochemical and Biophysical Characterisation of the Hepatitis E Virus Guanine-7-Methyltransferase
por: Hooda, Preeti, et al.
Publicado: (2022)

Hepatitis E Virus Cysteine Protease Has Papain Like Properties Validated by in silico Modeling and Cell-Free Inhibition Assays
por: Saraswat, Shweta, et al.
Publicado: (2020)

Inhibition of hepatitis E virus replication by proteasome inhibitor is nonspecific
por: Xu, Lei, et al.
Publicado: (2014)

Mutational analysis of hepatitis E virus ORF1 "Y-domain": Effects on RNA replication and virion infectivity
por: Parvez, Mohammad Khalid
Publicado: (2017)

Molecular Analysis and Modeling of Hepatitis E Virus Helicase and Identification of Novel Inhibitors by Virtual Screening
por: Parvez, Mohammad K., et al.
Publicado: (2018)

Inhibition of histone methyltransferase SETD8 represses DNA virus replication
por: Chen, Lin, et al.
Publicado: (2022)

Hepatitis E Virus Replication
por: LeDesma, Robert, et al.
Publicado: (2019)

The hepatitis E virus ORF1 ‘X-domain’ residues form a putative macrodomain protein/Appr-1″-pase catalytic-site, critical for viral RNA replication
por: Parvez, Mohammad Khalid
Publicado: (2015)

Expression and processing of the Hepatitis E virus ORF1 nonstructural polyprotein
por: Sehgal, Deepak, et al.
Publicado: (2006)

Molecular biology and replication of hepatitis E virus
por: Cao, Dianjun, et al.
Publicado: (2012)

Masitinib Inhibits Hepatitis A Virus Replication
por: Sasaki-Tanaka, Reina, et al.
Publicado: (2023)

The natural compound silvestrol inhibits hepatitis E virus (HEV) replication in vitro and in vivo
por: Todt, Daniel, et al.
Publicado: (2018)

Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy
por: Mizui, Tomokazu, et al.
Publicado: (2009)

Evidence for Independent Hepatitis E Virus Replication in the Brain
por: den Drijver, Evert P.M., et al.
Publicado: (2021)

Molecular modeling and analysis of hepatitis E virus (HEV) papain-like cysteine protease
por: Parvez, Mohammad Khalid, et al.
Publicado: (2014)

Efficient inhibition of hepatitis B virus replication by hepatitis delta virus ribozymes delivered by targeting retrovirus
por: Wang, Chuan-Xi, et al.
Publicado: (2010)

Baicalin inhibits the replication of the hepatitis B virus by targeting TRIM25
por: Fan, Xixi, et al.
Publicado: (2023)

Nucleoside analogue 2’-C-methylcytidine inhibits hepatitis E virus replication but antagonizes ribavirin
por: Qu, Changbo, et al.
Publicado: (2017)

Sequence to structure analysis of the ORF4 protein from Hepatitis E virus
por: Shafat, Zoya, et al.
Publicado: (2021)

Decoding the codon usage patterns in Y-domain region of hepatitis E viruses
por: Shafat, Zoya, et al.
Publicado: (2022)

The hepatitis E virus ORF1 X-domain N-terminal residues form a putative macrodomain protein/Appr-1″-pase catalytic-site, critical for RNA replication
por: Parvez, M.K.
Publicado: (2015)

Raloxifene inhibits hepatitis C virus infection and replication
por: Takeda, Midori, et al.
Publicado: (2012)

Entecavir combined with furin inhibitor simultaneously reduces hepatitis B virus replication and e antigen secretion
por: Yang, Hui Y, et al.
Publicado: (2014)

DNA Methyltransferase Inhibitor Zebularine Inhibits Human Hepatic Carcinoma Cells Proliferation and Induces Apoptosis
por: Nakamura, Kazuaki, et al.
Publicado: (2013)

Analysis of codon usage patterns in open reading frame 4 of hepatitis E viruses
por: Shafat, Zoya, et al.
Publicado: (2022)

Sequence to structural analysis of ORF5 protein in Norway rat Hepatitis E Virus
por: Shafat, Zoya, et al.
Publicado: (2022)

Repurposing of artesunate, an antimalarial drug, as a potential inhibitor of hepatitis E virus
por: Bhise, Neha, et al.
Publicado: (2023)

AGK2, A SIRT2 Inhibitor, Inhibits Hepatitis B Virus Replication In Vitro And In Vivo
por: Yu, Hai-Bo, et al.
Publicado: (2018)

Design, Synthesis and Discovery of N,N’‐Carbazoyl‐aryl‐urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication
por: Spizzichino, Sharon, et al.
Publicado: (2020)

Molecular characterization of hepatitis E virus ORF1 gene supports a papain-like cysteine protease (PCP)-domain activity
por: Parvez, Mohammad Khalid
Publicado: (2013)

Methyltransferase of a cell culture-adapted hepatitis E inhibits the MDA5 receptor signaling pathway
por: Myoung, Jinjong, et al.
Publicado: (2019)

Artemisinin Analogues as Potent Inhibitors of In Vitro Hepatitis C Virus Replication
por: Obeid, Susan, et al.
Publicado: (2013)

Hepatitis E virus replication and interferon responses in human placental cells
por: Knegendorf, Leonard, et al.
Publicado: (2018)

Inhibition of replication of hepatitis B virus using transcriptional repressors that target the viral DNA
por: Bloom, Kristie, et al.
Publicado: (2019)

Evidence of MAPK–JNK1/2 activation by hepatitis E virus ORF3 protein in cultured hepatoma cells
por: Parvez, Mohammad Khalid, et al.
Publicado: (2014)

Replication Inhibition of Hepatitis B Virus and Hepatitis C Virus in Co-Infected Patients in Chinese Population
por: Yu, Ge, et al.
Publicado: (2015)

Inhibition of duck hepatitis B virus replication by mimic peptides in vitro
por: JIA, HONGYU, et al.
Publicado: (2015)

Interleukin-34 inhibits hepatitis B virus replication in vitro and in vivo
por: Cheng, Sheng-Tao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jodk47g3ifmchsf4lpouin9g54