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Inhibition of Hepatitis E Virus Replication by Novel Inhibitor Targeting Methyltransferase
Hepatitis E Virus (HEV) is a quasi-enveloped virus having a single-stranded, positive-sense RNA genome (~7.2 kb), flanked with a 5′ methylated cap and a 3′ polyadenylated tail. The HEV open reading frame 1 (ORF1) encodes a 186-kDa polyprotein speculated to get processed and produce Methyltransferase...
Autores principales: | Hooda, Preeti, Chaudhary, Meenakshi, Parvez, Mohammad K., Sinha, Neha, Sehgal, Deepak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415367/ https://www.ncbi.nlm.nih.gov/pubmed/36016400 http://dx.doi.org/10.3390/v14081778 |
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