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HIV-Induced Hyperactivity of Striatal Neurons Is Associated with Dysfunction of Voltage-Gated Calcium and Potassium Channels at Middle Age

Despite combination antiretroviral therapy, HIV-associated neurocognitive disorders (HAND) occur in ~50% of people living with HIV (PLWH), which are associated with dysfunction of the corticostriatal pathway. The mechanism by which HIV alters the neuronal activity in the striatum is unknown. The goa...

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Detalles Bibliográficos
Autores principales: Khodr, Christina E., Chen, Lihua, Al-Harthi, Lena, Hu, Xiu-Ti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415409/
https://www.ncbi.nlm.nih.gov/pubmed/36005652
http://dx.doi.org/10.3390/membranes12080737