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Computer-Aided Screening of Phytoconstituents from Ocimum tenuiflorum against Diabetes Mellitus Targeting DPP4 Inhibition: A Combination of Molecular Docking, Molecular Dynamics, and Pharmacokinetics Approaches

Diabetes mellitus is a major global health concern in the current scenario which is chiefly characterized by the rise in blood sugar levels or hyperglycemia. In the context, DPP4 enzyme plays a critical role in glucose homeostasis. DPP4 targets and inactivates incretin hormones such as glucagon-like...

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Detalles Bibliográficos
Autores principales: Sajal, Harshit, Patil, Shashank M., Raj, Ranjith, Shbeer, Abdullah M., Ageel, Mohammed, Ramu, Ramith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415412/
https://www.ncbi.nlm.nih.gov/pubmed/36014373
http://dx.doi.org/10.3390/molecules27165133