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Computer-Aided Screening of Phytoconstituents from Ocimum tenuiflorum against Diabetes Mellitus Targeting DPP4 Inhibition: A Combination of Molecular Docking, Molecular Dynamics, and Pharmacokinetics Approaches
Diabetes mellitus is a major global health concern in the current scenario which is chiefly characterized by the rise in blood sugar levels or hyperglycemia. In the context, DPP4 enzyme plays a critical role in glucose homeostasis. DPP4 targets and inactivates incretin hormones such as glucagon-like...
Autores principales: | Sajal, Harshit, Patil, Shashank M., Raj, Ranjith, Shbeer, Abdullah M., Ageel, Mohammed, Ramu, Ramith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415412/ https://www.ncbi.nlm.nih.gov/pubmed/36014373 http://dx.doi.org/10.3390/molecules27165133 |
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