Altered TDP-43 Structure and Function: Key Insights into Aberrant RNA, Mitochondrial, and Cellular and Systemic Metabolism in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neuromuscular disorder with no cure available and limited treatment options. ALS is a highly heterogeneous disease, whereby patients present with vastly different phenotypes. Despite this heterogeneity, over 97% of patients will exhibit...

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Detalles Bibliográficos
Autores principales: Jiang, Leanne, Ngo, Shyuan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415507/
https://www.ncbi.nlm.nih.gov/pubmed/36005581
http://dx.doi.org/10.3390/metabo12080709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415507/
https://www.ncbi.nlm.nih.gov/pubmed/36005581
http://dx.doi.org/10.3390/metabo12080709

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