Synthesis and Biological Activity Characterization of Novel 5-Oxopyrrolidine Derivatives with Promising Anticancer and Antimicrobial Activity

The 1-(4-acetamidophenyl)-5-oxopyrrolidine carboxylic acid was applied for synthesizing derivatives bearing azole, diazole, and hydrazone moieties in the molecule. Modification of an acetamide fragment to the free amino group afforded compounds with two functional groups, which enabled to provide a...

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Detalles Bibliográficos
Autores principales: Kairytė, Karolina, Grybaitė, Birutė, Vaickelionienė, Rita, Sapijanskaitė-Banevič, Birutė, Kavaliauskas, Povilas, Mickevičius, Vytautas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415606/
https://www.ncbi.nlm.nih.gov/pubmed/36015119
http://dx.doi.org/10.3390/ph15080970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415606/
https://www.ncbi.nlm.nih.gov/pubmed/36015119
http://dx.doi.org/10.3390/ph15080970

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