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Hydrophobic Alpha-Helical Short Peptides in Overlapping Reading Frames of the Coronavirus Genome

In this study, we show that the coronavirus (CoV) genome may encode many functional hydrophobic alpha-helical peptides (HAHPs) in overlapping reading frames of major coronaviral proteins throughout the entire viral genome. These HAHPs can theoretically be expressed from non-canonical sub-genomic (sg...

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Detalles Bibliográficos
Autores principales: Okura, Takashi, Shirato, Kazuya, Kakizaki, Masatoshi, Sugimoto, Satoko, Matsuyama, Shutoku, Tanaka, Tomohisa, Kume, Yohei, Chishiki, Mina, Ono, Takashi, Moriishi, Kohji, Sonoyama, Masashi, Hosoya, Mitsuaki, Hashimoto, Koichi, Maenaka, Katsumi, Takeda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415614/
https://www.ncbi.nlm.nih.gov/pubmed/36014999
http://dx.doi.org/10.3390/pathogens11080877