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mRNA-Loaded Lipid Nanoparticles Targeting Immune Cells in the Spleen for Use as Cancer Vaccines

mRNA delivery has recently gained substantial interest for possible use in vaccines. Recently approved mRNA vaccines are administered intramuscularly where they transfect antigen-presenting cells (APCs) near the site of administration, resulting in an immune response. The spleen contains high number...

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Detalles Bibliográficos
Autores principales: Shimosakai, Ryoya, Khalil, Ikramy A., Kimura, Seigo, Harashima, Hideyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415712/
https://www.ncbi.nlm.nih.gov/pubmed/36015165
http://dx.doi.org/10.3390/ph15081017