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mRNA-Loaded Lipid Nanoparticles Targeting Immune Cells in the Spleen for Use as Cancer Vaccines
mRNA delivery has recently gained substantial interest for possible use in vaccines. Recently approved mRNA vaccines are administered intramuscularly where they transfect antigen-presenting cells (APCs) near the site of administration, resulting in an immune response. The spleen contains high number...
Autores principales: | Shimosakai, Ryoya, Khalil, Ikramy A., Kimura, Seigo, Harashima, Hideyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415712/ https://www.ncbi.nlm.nih.gov/pubmed/36015165 http://dx.doi.org/10.3390/ph15081017 |
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