Evaluation of PepT1 (SLC15A1) Substrate Characteristics of Therapeutic Cyclic Peptides

The human peptide transporter hPepT1 (SLC15A1), physiologically transporting dipeptides and tripeptides generated during food digestion, also plays a role in the uptake of small bioactive peptides and peptide-like drugs. Moreover, it might be addressed in prodrug strategies of poorly absorbed drugs....

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Detalles Bibliográficos
Autores principales: Bajraktari-Sylejmani, Gzona, von Linde, Teresa, Burhenne, Jürgen, Haefeli, Walter Emil, Sauter, Max, Weiss, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415731/
https://www.ncbi.nlm.nih.gov/pubmed/36015235
http://dx.doi.org/10.3390/pharmaceutics14081610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415731/
https://www.ncbi.nlm.nih.gov/pubmed/36015235
http://dx.doi.org/10.3390/pharmaceutics14081610

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