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Evaluation of PepT1 (SLC15A1) Substrate Characteristics of Therapeutic Cyclic Peptides
The human peptide transporter hPepT1 (SLC15A1), physiologically transporting dipeptides and tripeptides generated during food digestion, also plays a role in the uptake of small bioactive peptides and peptide-like drugs. Moreover, it might be addressed in prodrug strategies of poorly absorbed drugs....
Autores principales: | Bajraktari-Sylejmani, Gzona, von Linde, Teresa, Burhenne, Jürgen, Haefeli, Walter Emil, Sauter, Max, Weiss, Johanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415731/ https://www.ncbi.nlm.nih.gov/pubmed/36015235 http://dx.doi.org/10.3390/pharmaceutics14081610 |
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