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Amphotericin B-PEG Conjugates of ZnO Nanoparticles: Enhancement Antifungal Activity with Minimal Toxicity

Amphotericin B (AMB) is commonly used to treat life-threatening systemic fungal infections. AMB formulations that are more efficient and less nephrotoxic are currently unmet needs. In the current study, new ZnO-PEGylated AMB (ZnO-AMB-PEG) nanoparticles (NPs) were synthesized and their antifungal eff...

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Detalles Bibliográficos
Autores principales: Alshahrani, Saad M., Khafagy, El-Sayed, Riadi, Yassine, Al Saqr, Ahmed, Alfadhel, Munerah M., Hegazy, Wael A. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415822/
https://www.ncbi.nlm.nih.gov/pubmed/36015271
http://dx.doi.org/10.3390/pharmaceutics14081646