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Efficacy and Safety of Trametinib in Neurofibromatosis Type 1-Associated Plexiform Neurofibroma and Low-Grade Glioma: A Systematic Review and Meta-Analysis

Trametinib has been used in neurofibromatosis type 1 (NF1) patients, especially those with unresectable nerve tumors, but no systematic review based on the latest studies has been published. We conducted this meta-analysis to evaluate the effectiveness and safety of trametinib in treating NF1-relate...

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Detalles Bibliográficos
Autores principales: Wang, Dun, Ge, Lingling, Guo, Zizhen, Li, Yuehua, Zhu, Beiyao, Wang, Wei, Wei, Chengjiang, Li, Qingfeng, Wang, Zhichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415905/
https://www.ncbi.nlm.nih.gov/pubmed/36015104
http://dx.doi.org/10.3390/ph15080956