A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro

There is a clear need for novel antiviral concepts to control SARS-CoV-2 infection. Based on the promising anti-coronavirus activity observed for a class of 1,4,4-trisubstituted piperidines, we here conducted a detailed analysis of the structure–activity relationship of these structurally unique inh...

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Detalles Bibliográficos
Autores principales: De Castro, Sonia, Stevaert, Annelies, Maldonado, Miguel, Delpal, Adrien, Vandeput, Julie, Van Loy, Benjamin, Eydoux, Cecilia, Guillemot, Jean-Claude, Decroly, Etienne, Gago, Federico, Canard, Bruno, Camarasa, Maria-Jose, Velázquez, Sonsoles, Naesens, Lieve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416004/
https://www.ncbi.nlm.nih.gov/pubmed/36015168
http://dx.doi.org/10.3390/ph15081021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416004/
https://www.ncbi.nlm.nih.gov/pubmed/36015168
http://dx.doi.org/10.3390/ph15081021

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