Development and In Vitro-Ex Vivo Evaluation of Novel Polymeric Nasal Donepezil Films for Potential Use in Alzheimer’s Disease Using Experimental Design

The objective and novelty of the present study is the development and optimization of innovative nasal film of Donepezil hydrochloride (DH) for potential use in Alzheimer’s disease. Hydroxypropyl-methyl-cellulose E50 (factor A) nasal films, with Polyethylene glycol 400 as plasticizer (factor B), and...

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Detalles Bibliográficos
Autores principales: Papakyriakopoulou, Paraskevi, Rekkas, Dimitrios M., Colombo, Gaia, Valsami, Georgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416078/
https://www.ncbi.nlm.nih.gov/pubmed/36015368
http://dx.doi.org/10.3390/pharmaceutics14081742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416078/
https://www.ncbi.nlm.nih.gov/pubmed/36015368
http://dx.doi.org/10.3390/pharmaceutics14081742

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