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Automated Radiosynthesis, Preliminary In Vitro/In Vivo Characterization of OncoFAP-Based Radiopharmaceuticals for Cancer Imaging and Therapy

FAP-targeted radiopharmaceuticals represent a breakthrough in cancer imaging and a viable option for therapeutic applications. OncoFAP is an ultra-high-affinity ligand of FAP with a dissociation constant of 680 pM. OncoFAP has been recently discovered and clinically validated for PET imaging procedu...

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Detalles Bibliográficos
Autores principales: Bartoli, Francesco, Elsinga, Philip, Nazario, Luiza Reali, Zana, Aureliano, Galbiati, Andrea, Millul, Jacopo, Migliorini, Francesca, Cazzamalli, Samuele, Neri, Dario, Slart, Riemer H. J. A., Erba, Paola Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416253/
https://www.ncbi.nlm.nih.gov/pubmed/36015106
http://dx.doi.org/10.3390/ph15080958