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Translating the Manufacture of Immunotherapeutic PLGA Nanoparticles from Lab to Industrial Scale: Process Transfer and In Vitro Testing

Poly(lactic-co-glycolic acid) (PLGA) nanoparticle-based drug delivery systems are known to offer a plethora of potential therapeutic benefits. However, challenges related to large-scale manufacturing, such as the difficulty of reproducing complex formulations and high manufacturing costs, hinder the...

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Detalles Bibliográficos
Autores principales: Operti, Maria Camilla, Bernhardt, Alexander, Pots, Jeanette, Sincari, Vladimir, Jager, Eliezer, Grimm, Silko, Engel, Andrea, Benedikt, Anne, Hrubý, Martin, De Vries, Ingrid Jolanda M., Figdor, Carl G., Tagit, Oya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416304/
https://www.ncbi.nlm.nih.gov/pubmed/36015316
http://dx.doi.org/10.3390/pharmaceutics14081690