Comparing the Phenylalanine/Tyrosine Pathway and Related Factors between Keratopathy and No-Keratopathy Groups as Well as between Genders in Alkaptonuria during Nitisinone Treatment

Nitisinone (NIT) causes tyrosinaemia and corneal keratopathy (KP), especially in men. However, the adaptation within the phenylalanine (PHE)/tyrosine (TYR) catabolic pathway during KP is not understood. The objective of this study is to assess potential differences in the PHE/TYR pathway during KP a...

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Detalles Bibliográficos
Autores principales: Ranganath, Lakshminarayan R., Milan, Anna M., Hughes, Andrew T., Davison, Andrew S., Khedr, Milad, Imrich, Richard, Rudebeck, Mattias, Olsson, Birgitta, Norman, Brendan P., Bou-Gharios, George, Gallagher, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416442/
https://www.ncbi.nlm.nih.gov/pubmed/36005644
http://dx.doi.org/10.3390/metabo12080772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416442/
https://www.ncbi.nlm.nih.gov/pubmed/36005644
http://dx.doi.org/10.3390/metabo12080772

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