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Simultaneous Analysis of the p16 Gene and Protein in Canine Lymphoma Cells and Their Correlation with pRb Phosphorylation

SIMPLE SUMMARY: Lymphoma is one of the most frequently diagnosed malignancies in dogs. The most common epigenetic alteration is gene methylation. Methylation of the p16 gene leads to decreased expression of its protein. The p16 protein inhibits the activity of cyclin-dependent kinase, as a negative...

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Detalles Bibliográficos
Autores principales: Maylina, Leni, Kambayashi, Satoshi, Baba, Kenji, Okuda, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416461/
https://www.ncbi.nlm.nih.gov/pubmed/36006308
http://dx.doi.org/10.3390/vetsci9080393