Virtual Screening for FDA-Approved Drugs That Selectively Inhibit Arginase Type 1 and 2

Arginases are often overexpressed in human diseases, and they are an important target for developing anti-aging and antineoplastic drugs. Arginase type 1 (ARG1) is a cytosolic enzyme, and arginase type 2 (ARG2) is a mitochondrial one. In this study, a dataset containing 2115-FDA-approved drug molecu...

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Detalles Bibliográficos
Autores principales: Detroja, Trishna Saha, Samson, Abraham O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416497/
https://www.ncbi.nlm.nih.gov/pubmed/36014374
http://dx.doi.org/10.3390/molecules27165134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416497/
https://www.ncbi.nlm.nih.gov/pubmed/36014374
http://dx.doi.org/10.3390/molecules27165134

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