Improvements to Hybridization-Ligation ELISA Methods to Overcome Bioanalytical Challenges Posed by Novel Oligonucleotide Therapeutics

As oligonucleotides (ONs) and similar nucleic acid therapeutic modalities enter development pipelines, there is continual need to develop bioanalytical methodologies addressing unique challenges they pose. Novel ONs back bone chemistries, especially those enabling stereochemical control, and base mo...

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Detalles Bibliográficos
Autores principales: Haegele, Joseph A., Boyanapalli, Ramakrishna, Goyal, Jaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416565/
https://www.ncbi.nlm.nih.gov/pubmed/35404142
http://dx.doi.org/10.1089/nat.2021.0100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416565/
https://www.ncbi.nlm.nih.gov/pubmed/35404142
http://dx.doi.org/10.1089/nat.2021.0100

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