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Development and Validation of an In-House Real-Time Reverse-Transcriptase Polymerase Chain Reaction Assay for SARS-CoV-2 Omicron Lineage Subtyping between BA.1 and BA.2

In order to rapidly differentiate sublineages BA.1 and BA.2 of the SARS-CoV-2 variant of concern Omicron, we developed a real-time reverse-transcriptase polymerase chain reaction to target the discriminatory spike protein deletion at amino acid position 69–70 (S:del69–70). Compared to the gold stand...

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Detalles Bibliográficos
Autores principales: Pham, David, Maddocks, Susan, Dwyer, Dominic E., Sintchenko, Vitali, Kok, Jen, Rockett, Rebecca J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416591/
https://www.ncbi.nlm.nih.gov/pubmed/36016382
http://dx.doi.org/10.3390/v14081760