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The Effect of 1,2,4-Triazole-3-thiol Derivatives Bearing Hydrazone Moiety on Cancer Cell Migration and Growth of Melanoma, Breast, and Pancreatic Cancer Spheroids

4-Phenyl-3-[2-(phenylamino)ethyl]-1H-1,2,4-triazole-5(4H)-thione was used as a starting compound for the synthesis of the corresponding 1,2,4-triazol-3-ylthioacetohydrazide, which reacts with isatins and various aldehydes bearing aromatic and heterocyclic moieties provided target hydrazones. Their c...

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Detalles Bibliográficos
Autores principales: Šermukšnytė, Aida, Kantminienė, Kristina, Jonuškienė, Ilona, Tumosienė, Ingrida, Petrikaitė, Vilma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416745/
https://www.ncbi.nlm.nih.gov/pubmed/36015174
http://dx.doi.org/10.3390/ph15081026