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Tumor Microenvironment-Responsive Polymeric iRGD and Doxorubicin Conjugates Reduce Spontaneous Lung Metastasis in an Orthotopic Breast Cancer Model

Tremendous progress has been made in the field of nanomedicine for cancer treatment. However, most of the research to date has been focused on inhibiting primary tumor growth with comparatively less efforts directed towards managing tumor metastasis. Here, we introduce a polymeric conjugate P-DOX-iR...

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Detalles Bibliográficos
Autores principales: Peng, Zheng-Hong, Jogdeo, Chinmay M., Li, Jing, Xie, Ying, Wang, Yazhe, Sheinin, Yuri M., Kopeček, Jindřich, Oupický, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416753/
https://www.ncbi.nlm.nih.gov/pubmed/36015351
http://dx.doi.org/10.3390/pharmaceutics14081725