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Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas

Infantile hemangiomas (IH) leave sequelae after involution. Topical application of timolol maleate (TM) is the mainstream treatment for superficial lesions but is limited by its low penetrable properties. We aimed to develop a superior skin permeation drug while maintaining the therapeutic propertie...

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Detalles Bibliográficos
Autores principales: Chang, Shih-Jen, Wang, Huiyuan, Chen, Jialin, Chen, Qianyi, Chang, Lei, Huang, Yongzhuo, Qiu, Yajing, Lin, Xiaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416783/
https://www.ncbi.nlm.nih.gov/pubmed/36015233
http://dx.doi.org/10.3390/pharmaceutics14081607