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Maintenance of Hypoimmunogenic Features via Regulation of Endogenous Antigen Processing and Presentation Machinery

Universally acceptable donor cells have been developed to address the unmet need for immunotypically matched materials for regenerative medicine. Since forced expression of hypoimmunogenic genes represses the immune response, we established universal pluripotent stem cells (PSCs) by replacing endoge...

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Detalles Bibliográficos
Autores principales: An, Ju-Hyun, Koh, Hyebin, Ahn, Yujin, Kim, Jieun, Han, A-Reum, Lee, Ji Yoon, Kim, Sun-Uk, Lee, Jong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416868/
https://www.ncbi.nlm.nih.gov/pubmed/36032723
http://dx.doi.org/10.3389/fbioe.2022.936584