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Maintenance of Hypoimmunogenic Features via Regulation of Endogenous Antigen Processing and Presentation Machinery
Universally acceptable donor cells have been developed to address the unmet need for immunotypically matched materials for regenerative medicine. Since forced expression of hypoimmunogenic genes represses the immune response, we established universal pluripotent stem cells (PSCs) by replacing endoge...
Autores principales: | An, Ju-Hyun, Koh, Hyebin, Ahn, Yujin, Kim, Jieun, Han, A-Reum, Lee, Ji Yoon, Kim, Sun-Uk, Lee, Jong-Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416868/ https://www.ncbi.nlm.nih.gov/pubmed/36032723 http://dx.doi.org/10.3389/fbioe.2022.936584 |
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