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Combining ablative radiotherapy and anti CD47 monoclonal antibody improves infiltration of immune cells in tumor microenvironments

Radiotherapy as an anti-tumor treatment can stimulate the immune system. However, irradiated tumor cells express CD47 to escape the anti-tumor immune response. Anti- CD47 Immunotherapy is a possible way to tackle this problem. This study evaluated the effect of single high dose radiotherapy combined...

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Detalles Bibliográficos
Autores principales: Rostami, Elham, Bakhshandeh, Mohsen, Ghaffari-Nazari, Haniyeh, Alinezhad, Maedeh, Alimohammadi, Masoumeh, Alimohammadi, Reza, Mahmoodi Chalbatani, Ghanbar, Hejazi, Ehsan, Webster, Thomas J., Tavakkol-Afshari, Jalil, Jalali, Seyed Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417014/
https://www.ncbi.nlm.nih.gov/pubmed/36018888
http://dx.doi.org/10.1371/journal.pone.0273547