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Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA
Functional RNAs fold through complex pathways that can contain misfolded “kinetic traps.” A complete model of RNA folding requires understanding the formation of these misfolded states, but they are difficult to characterize because of their transient and potentially conformationally dynamic nature....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417180/ https://www.ncbi.nlm.nih.gov/pubmed/36026457 http://dx.doi.org/10.1126/sciadv.abq4144 |