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RORγt expression in mature T(H)17 cells safeguards their lineage specification by inhibiting conversion to T(H)2 cells
RORγt is the lineage-specific transcription factor for T helper 17 (T(H)17) cells and an attractive drug target for treating T(H)17-associated diseases. Although the critical role of RORγt in early T(H)17 cell differentiation has been well recognized, its function in mature T(H)17 cell maintenance r...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417185/ https://www.ncbi.nlm.nih.gov/pubmed/36026450 http://dx.doi.org/10.1126/sciadv.abn7774 |