mtDNA variability determines spontaneous joint aging damage in a conplastic mouse model

Mitochondria and mtDNA variations contribute to specific aspects of the aging process. Here, we aimed to investigate the influence of mtDNA variation on joint damage in a model of aging using conplastic mice. A conplastic (BL/6(NZB)) mouse strain was developed with the C57BL/6JOlaHsd nuclear genome...

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Detalles Bibliográficos
Autores principales: Scotece, Morena, Vaamonde-García, Carlos, Lechuga-Vieco, Ana Victoria, Cortés, Alberto Centeno, Gómez, María Concepción Jiménez, Filgueira-Fernández, Purificación, Rego-Pérez, Ignacio, Enríquez, José Antonio, Blanco, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417242/
https://www.ncbi.nlm.nih.gov/pubmed/35779570
http://dx.doi.org/10.18632/aging.204153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417242/
https://www.ncbi.nlm.nih.gov/pubmed/35779570
http://dx.doi.org/10.18632/aging.204153

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