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Spontaneous self-assembly of amyloid β (1–40) into dimers

The self-assembly and fibrillation of amyloid β (Aβ) proteins is the neuropathological hallmark of Alzheimer's disease. However, the molecular mechanism of how disordered monomers assemble into aggregates remains largely unknown. In this work, we characterize the assembly of Aβ (1–40) monomers...

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Detalles Bibliográficos
Autores principales: Hashemi, Mohtadin, Zhang, Yuliang, Lv, Zhengjian, Lyubchenko, Yuri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417245/
https://www.ncbi.nlm.nih.gov/pubmed/36132110
http://dx.doi.org/10.1039/c9na00380k