An auto-inhibited state of protein kinase G and implications for selective activation

Cyclic GMP-dependent protein kinases (PKGs) are key mediators of the nitric oxide/cyclic guanosine monophosphate (cGMP) signaling pathway that regulates biological functions as diverse as smooth muscle contraction, cardiac function, and axon guidance. Understanding how cGMP differentially triggers m...

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Detalles Bibliográficos
Autores principales: Sharma, Rajesh, Kim, Jeong Joo, Qin, Liying, Henning, Philipp, Akimoto, Madoka, VanSchouwen, Bryan, Kaur, Gundeep, Sankaran, Banumathi, MacKenzie, Kevin R, Melacini, Giuseppe, Casteel, Darren E, Herberg, Friedrich W, Kim, Choel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417419/
https://www.ncbi.nlm.nih.gov/pubmed/35929723
http://dx.doi.org/10.7554/eLife.79530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417419/
https://www.ncbi.nlm.nih.gov/pubmed/35929723
http://dx.doi.org/10.7554/eLife.79530

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