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Dscam1 Has Diverse Neuron Type-Specific Functions in the Developing Drosophila CNS

Two key features endow Drosophila Down syndrome cell adhesion molecule 1 (Dscam1) with the potential to provide a ubiquitous code for neuronal arbor self-avoidance. First, Dscam1 contains three large cassettes of alternative exons, so that stochastic alternative splicing yields 19,008 Dscam1 isoform...

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Detalles Bibliográficos
Autores principales: Wilhelm, Nicole, Kumari, Shikha, Krick, Niklas, Rickert, Christof, Duch, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417601/
https://www.ncbi.nlm.nih.gov/pubmed/35981870
http://dx.doi.org/10.1523/ENEURO.0255-22.2022