Cargando…

Dscam1 Has Diverse Neuron Type-Specific Functions in the Developing Drosophila CNS

Two key features endow Drosophila Down syndrome cell adhesion molecule 1 (Dscam1) with the potential to provide a ubiquitous code for neuronal arbor self-avoidance. First, Dscam1 contains three large cassettes of alternative exons, so that stochastic alternative splicing yields 19,008 Dscam1 isoform...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wilhelm, Nicole, Kumari, Shikha, Krick, Niklas, Rickert, Christof, Duch, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2022
Materias:	Research Article: New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417601/ https://www.ncbi.nlm.nih.gov/pubmed/35981870 http://dx.doi.org/10.1523/ENEURO.0255-22.2022

Ejemplares similares

A chelicerate-specific burst of nonclassical Dscam diversity
por: Cao, Guozheng, et al.
Publicado: (2018)

Progressive derivation of serially homologous neuroblast lineages in the gnathal CNS of Drosophila
por: Rickert, Christof, et al.
Publicado: (2018)

Dscam2 affects visual perception in Drosophila melanogaster
por: Bosch, Danny S., et al.
Publicado: (2015)

DSCAM regulates delamination of neurons in the developing midbrain
por: Arimura, Nariko, et al.
Publicado: (2020)

A systematic CRISPR screen reveals redundant and specific roles for Dscam1 isoform diversity in neuronal wiring
por: Dong, Haiyang, et al.
Publicado: (2023)

Improvement of Dscam homophilic binding affinity throughout Drosophila evolution
por: Wang, Guang-Zhong, et al.
Publicado: (2014)

Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent
por: Andrews, Melissa R., et al.
Publicado: (2016)

Dysfunction of NMDA receptors in neuronal models of an autism spectrum disorder patient with a DSCAM mutation and in Dscam-knockout mice
por: Lim, Chae-Seok, et al.
Publicado: (2021)

A Novel Mouse Dscam Mutation Inhibits Localization and Shedding of DSCAM
por: Schramm, R. Dee, et al.
Publicado: (2012)

Population Genetics of Duplicated Alternatively Spliced Exons of the Dscam Gene in Daphnia and Drosophila
por: Brites, Daniela, et al.
Publicado: (2011)

Pathogen-Specific Binding Soluble Down Syndrome Cell Adhesion Molecule (Dscam) Regulates Phagocytosis via Membrane-Bound Dscam in Crab
por: Li, Xue-Jie, et al.
Publicado: (2018)

Dynein-Dynactin Complex Is Essential for Dendritic Restriction of TM1-Containing Drosophila Dscam
por: Yang, Jacob Shun-Jen, et al.
Publicado: (2008)

A Novel Neuron-Specific Regulator of the V-ATPase in Drosophila
por: Dulac, Amina, et al.
Publicado: (2021)

Integration of Circadian Clock Information in the Drosophila Circadian Neuronal Network
por: Ahmad, Myra, et al.
Publicado: (2021)

Alternative splicing of the Anopheles gambiae Dscam gene in diverse Plasmodium falciparum infections
por: Smith, Paul H, et al.
Publicado: (2011)

Drosophila as a Model for MECP2 Gain of Function in Neurons
por: Vonhoff, Fernando, et al.
Publicado: (2012)

The evolution of Dscam genes across the arthropods
por: Armitage, Sophie AO, et al.
Publicado: (2012)

DSCAMs: restoring balance to developmental forces
por: Garrett, Andrew M., et al.
Publicado: (2012)

Trans-splicing facilitated by RNA pairing greatly expands sDscam isoform diversity but not homophilic binding specificity
por: Hou, Shouqing, et al.
Publicado: (2022)

Differential Contributions of Olfactory Receptor Neurons in a Drosophila Olfactory Circuit
por: Newquist, Gunnar, et al.
Publicado: (2016)

Rapid degeneration of Drosophila olfactory neurons in Orco mutant maxillary palps
por: Task, Darya, et al.
Publicado: (2021)

Quantitative Profiling of Drosophila melanogaster Dscam1 Isoforms Reveals No Changes in Splicing after Bacterial Exposure
por: Armitage, Sophie A. O., et al.
Publicado: (2014)

Deterministic splicing of Dscam2 is regulated by Muscleblind
por: Li, Joshua Shing Shun, et al.
Publicado: (2019)

A Review on the Carcinogenic Roles of DSCAM-AS1
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2021)

Wakefulness Is Promoted during Day Time by PDFR Signalling to Dopaminergic Neurons in Drosophila melanogaster
por: Potdar, Sheetal, et al.
Publicado: (2018)

Reducing the expression of the Numb adaptor protein in neurons increases the searching behavior of Drosophila larvae
por: Galbraith, Andrew, et al.
Publicado: (2021)

Newly Identified Electrically Coupled Neurons Support Development of the Drosophila Giant Fiber Model Circuit
por: Kennedy, Tyler, et al.
Publicado: (2018)

Cis mutagenesis in vivo reveals extensive noncanonical functions of Dscam1 isoforms in neuronal wiring
por: Zhang, Shixin, et al.
Publicado: (2023)

A third copy of the Down syndrome cell adhesion molecule (Dscam) causes synaptic and locomotor dysfunction in Drosophila
por: Lowe, Simon A., et al.
Publicado: (2018)

Ovarian somatic Piwi regulates nurse cell proliferation and oocyte specification in Drosophila
por: Gonzalez, Lauren E, et al.
Publicado: (2020)

Isoform specific knockdown of the ETS transcription factor Pointed in Drosophila S2 cells
por: Vivekanand, Pavithra
Publicado: (2023)

Bacteria-Induced Dscam Isoforms of the Crustacean, Pacifastacus leniusculus
por: Watthanasurorot, Apiruck, et al.
Publicado: (2011)

Sphingolipid-dependent Dscam sorting regulates axon segregation
por: Goyal, Gaurav, et al.
Publicado: (2019)

Role of DSCAM in the Development of Neural Control of Movement and Locomotion
por: Lemieux, Maxime, et al.
Publicado: (2021)

Dscam1: Is It a Ubiquitous Code for Dendritic Arborization?
por: Kirkise, Nikita, et al.
Publicado: (2023)

Structural basis for the self-recognition of sDSCAM in Chelicerata
por: Cheng, Jie, et al.
Publicado: (2023)

Loss of dpy-2 and dpy-9 has stage-specific effects on DBL-1 pathway signaling
por: Lakdawala, Mohammed Farhan, et al.
Publicado: (2019)

dSTIM- and Ral/Exocyst-Mediated Synaptic Release from Pupal Dopaminergic Neurons Sustains Drosophila Flight
por: Richhariya, Shlesha, et al.
Publicado: (2018)

Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor-Driven Behavioral Kinetics
por: Raccuglia, Davide, et al.
Publicado: (2016)

Examining Sleep Modulation by Drosophila Ellipsoid Body Neurons
por: Singh, Prabhjit, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8ib7sh3963d59ermsfuul1sjni