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NCX1 coupled with TRPC1 to promote gastric cancer via Ca(2+)/AKT/β-catenin pathway

Plasma membrane Na(+)/Ca(2+) exchanger 1 (NCX1) is a bidirectional ion transporter to operate in Ca(2+) entry or exit modes, and TRPC1 is Ca(2+)-permeable channel. Both NCX1 and TRPC1 play critical roles in maintaining cytosolic free Ca(2+) ([Ca(2+)](cyt)) homeostasis in mammalian cells. Although ei...

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Detalles Bibliográficos
Autores principales: Wan, Hanxing, Gao, Nannan, Lu, Wei, Lu, Cheng, Chen, Jun, Wang, Yimin, Dong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418000/
https://www.ncbi.nlm.nih.gov/pubmed/35882979
http://dx.doi.org/10.1038/s41388-022-02412-9