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Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine

Plasmodium vivax is a malaria-causing pathogen that establishes a dormant form in the liver (the hypnozoite), which can activate weeks, months, or years after the primary infection to cause a relapse, characterized by secondary blood-stage infection. These asymptomatic and undetectable latent liver...

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Detalles Bibliográficos
Autores principales: Flannery, Erika L., Kangwanrangsan, Niwat, Chuenchob, Vorada, Roobsoong, Wanlapa, Fishbaugher, Matthew, Zhou, Kevin, Billman, Zachary P., Martinson, Thomas, Olsen, Tayla M., Schäfer, Carola, Campo, Brice, Murphy, Sean C., Mikolajczak, Sebastian A., Kappe, Stefan H.I., Sattabongkot, Jetsumon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418049/
https://www.ncbi.nlm.nih.gov/pubmed/36092359
http://dx.doi.org/10.1016/j.omtm.2022.07.016