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Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine
Plasmodium vivax is a malaria-causing pathogen that establishes a dormant form in the liver (the hypnozoite), which can activate weeks, months, or years after the primary infection to cause a relapse, characterized by secondary blood-stage infection. These asymptomatic and undetectable latent liver...
Autores principales: | Flannery, Erika L., Kangwanrangsan, Niwat, Chuenchob, Vorada, Roobsoong, Wanlapa, Fishbaugher, Matthew, Zhou, Kevin, Billman, Zachary P., Martinson, Thomas, Olsen, Tayla M., Schäfer, Carola, Campo, Brice, Murphy, Sean C., Mikolajczak, Sebastian A., Kappe, Stefan H.I., Sattabongkot, Jetsumon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418049/ https://www.ncbi.nlm.nih.gov/pubmed/36092359 http://dx.doi.org/10.1016/j.omtm.2022.07.016 |
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