MiR-6511b-5p suppresses metastasis of pMMR colorectal cancer through methylation of CD44 by directly targeting BRG1

PURPOSE: Distal metastases are a major cause of poor prognosis in colorectal cancer patients. Approximately 95% of metastatic colorectal cancers are defined as DNA mismatch repair proficient (pMMR). Our previous study found that miR-6511b-5p was downregulated in pMMR colorectal cancer. However, the...

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Detalles Bibliográficos
Autores principales: Sun, JinMing, Ye, Ling, Shi, Yuan, Wang, XingWei, Zhao, XiaFei, Ren, ShengYong, Fan, JunWei, Shao, HuanZhang, Qin, BingYu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418090/
https://www.ncbi.nlm.nih.gov/pubmed/35590122
http://dx.doi.org/10.1007/s12094-022-02845-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418090/
https://www.ncbi.nlm.nih.gov/pubmed/35590122
http://dx.doi.org/10.1007/s12094-022-02845-4

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