Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson’s disease

PURPOSE: Altered serotonergic neurotransmission may contribute to the non-motor features commonly associated with Parkinson’s disease (PD) such as sleep disorders. The 5-hydroxytryptophan (5-HTP) is the intermediate metabolite of l-tryptophan in the production of serotonin and melatonin. The purpose...

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Detalles Bibliográficos
Autores principales: Meloni, Mario, Figorilli, Michela, Carta, Manolo, Tamburrino, Ludovica, Cannas, Antonino, Sanna, Fabrizio, Defazio, Giovanni, Puligheddu, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Sleep Breathing Physiology and Disorders • Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418091/
https://www.ncbi.nlm.nih.gov/pubmed/34403081
http://dx.doi.org/10.1007/s11325-021-02417-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418091/
https://www.ncbi.nlm.nih.gov/pubmed/34403081
http://dx.doi.org/10.1007/s11325-021-02417-w

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