Cargando…

Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson’s disease

PURPOSE: Altered serotonergic neurotransmission may contribute to the non-motor features commonly associated with Parkinson’s disease (PD) such as sleep disorders. The 5-hydroxytryptophan (5-HTP) is the intermediate metabolite of l-tryptophan in the production of serotonin and melatonin. The purpose...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meloni, Mario, Figorilli, Michela, Carta, Manolo, Tamburrino, Ludovica, Cannas, Antonino, Sanna, Fabrizio, Defazio, Giovanni, Puligheddu, Monica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Sleep Breathing Physiology and Disorders • Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418091/ https://www.ncbi.nlm.nih.gov/pubmed/34403081 http://dx.doi.org/10.1007/s11325-021-02417-w

Ejemplares similares

Respiratory safety of lemborexant in healthy adult and elderly subjects with mild obstructive sleep apnea: A randomized, double‐blind, placebo‐controlled, crossover study
por: Cheng, Jocelyn Y., et al.
Publicado: (2020)

Sleep‐related hypermotor epilepsy and non‐rapid eye movement parasomnias: Differences in the periodic and aperiodic component of the electroencephalographic power spectra
por: Pani, Sara M., et al.
Publicado: (2021)

Objective measurement of compliance during oral appliance therapy for sleep-disordered breathing
por: Vanderveken, Olivier M, et al.
Publicado: (2013)

Displacement of the hyoid bone by muscle paralysis and lung volume increase: the effects of obesity and obstructive sleep apnea
por: Kohno, Akane, et al.
Publicado: (2018)

Obstructive sleep apnea is associated with coronary microvascular dysfunction: A systematic review from a clinical perspective
por: Zhang, Rui‐Heng, et al.
Publicado: (2020)

Determinants of depressive mood in coronary artery disease patients with obstructive sleep apnea and response to continuous positive airway pressure treatment in non‐sleepy and sleepy phenotypes in the RICCADSA cohort
por: Balcan, Baran, et al.
Publicado: (2019)

Long-term efficacy and safety of phrenic nerve stimulation for the treatment of central sleep apnea
por: Fox, Henrik, et al.
Publicado: (2019)

Assessment of obstructive sleep apnea-related sleep fragmentation utilizing deep learning-based sleep staging from photoplethysmography
por: Huttunen, Riku, et al.
Publicado: (2021)

Swallowing and aspiration during sleep in patients with obstructive sleep apnea versus control individuals
por: Kohno, Akane, et al.
Publicado: (2022)

Algorithm for automatic detection of self-similarity and prediction of residual central respiratory events during continuous positive airway pressure
por: Oppersma, Eline, et al.
Publicado: (2020)

A multicentric validation study of a novel home sleep apnea test based on peripheral arterial tonometry
por: Van Pee, Bart, et al.
Publicado: (2022)

Improvements in cognitive function and quantitative sleep electroencephalogram in obstructive sleep apnea after six months of continuous positive airway pressure treatment
por: D’Rozario, Angela L, et al.
Publicado: (2022)

Effect of adaptive servo ventilation on central sleep apnea and sleep structure in systolic heart failure patients: polysomnography data from the SERVE‐HF major sub study
por: Tamisier, Renaud, et al.
Publicado: (2022)

Abnormal brain iron accumulation in obstructive sleep apnea: A quantitative MRI study in the HypnoLaus cohort
por: Marchi, Nicola Andrea, et al.
Publicado: (2022)

Self‐reported symptoms of sleep‐disordered breathing and risk of cardiovascular diseases: Observational and Mendelian randomization findings
por: Titova, Olga E., et al.
Publicado: (2022)

Correlates of excessive daytime sleepiness in obstructive sleep apnea: Results from the nationwide SESAR cohort including 34,684 patients
por: Ulander, Martin, et al.
Publicado: (2022)

In search of a better CPAP interface: A network meta‐analysis comparing nasal masks, nasal pillows and oronasal masks
por: Chen, Li‐Yang, et al.
Publicado: (2022)

Discovery of genomic loci associated with sleep apnea risk through multi-trait GWAS analysis with snoring
por: Campos, Adrian I, et al.
Publicado: (2022)

The effect of obstructive sleep apnea therapy on cardiovascular autonomic function: a systematic review and meta-analysis
por: Dissanayake, Hasthi U, et al.
Publicado: (2022)

Comparative associations of oximetry patterns in Obstructive Sleep Apnea with incident cardiovascular disease
por: Sutherland, Kate, et al.
Publicado: (2022)

Multimodal phenotypic labelling using drug‐induced sleep endoscopy, awake nasendoscopy and computational fluid dynamics for the prediction of mandibular advancement device treatment outcome: a prospective study
por: Van den Bossche, Karlien, et al.
Publicado: (2022)

Transvenous phrenic nerve stimulation is associated with normalization of nocturnal heart rate perturbations in patients with central sleep apnea
por: Baumert, Mathias, et al.
Publicado: (2023)

How does obstructive sleep apnea alter cerebral hemodynamics?
por: Gregori-Pla, Clara, et al.
Publicado: (2023)

Overnight declarative memory consolidation and non-rapid eye movement sleep electroencephalographic oscillations in older adults with obstructive sleep apnea
por: Teh, Jun Z, et al.
Publicado: (2023)

Treatment outcome of oral appliance in patients with REM-related obstructive sleep apnea
por: Nishio, Yoshitomo, et al.
Publicado: (2019)

PAP treatment in patients with OSA does not induce long‐term nasal obstruction
por: Värendh, Maria, et al.
Publicado: (2018)

The association between plasma metabolites and sleep quality in the Southall and Brent Revisited (SABRE) Study: A cross‐sectional analysis
por: Topriceanu, Constantin‐Cristian, et al.
Publicado: (2020)

Communication during the initial visit to a CPAP clinic Practitioners’ experiences of facilitators and barriers when talking to patients with obstructive sleep apnea
por: Broström, Anders, et al.
Publicado: (2020)

Effects of oral appliance treatment on inflammatory biomarkers in obstructive sleep apnea: A randomised controlled trial
por: Hedberg, Pär, et al.
Publicado: (2020)

Central apnea and periodic breathing in children with underlying conditions
por: Ghirardo, Sergio, et al.
Publicado: (2021)

Rapid eye movement sleep apnea and carotid intima thickness in men and women: a SHE‐MUSTACHE cohort study
por: Ljunggren, Mirjam, et al.
Publicado: (2022)

Influence and implications of the renin–angiotensin–aldosterone system in obstructive sleep apnea: An updated systematic review and meta‐analysis
por: Loh, Huai Heng, et al.
Publicado: (2022)

Association Between Serum Lipid Profile and Obstructive Respiratory Events During REM and Non-REM Sleep
por: Bikov, Andras, et al.
Publicado: (2019)

Considering REM Sleep Behavior Disorder in the Management of Parkinson’s Disease
por: Figorilli, Michela, et al.
Publicado: (2023)

A cohort study to identify simple clinical tests for chronic respiratory failure in obese patients with sleep-disordered breathing
por: Mandal, S, et al.
Publicado: (2014)

The psycho-sensory wake drive—a power source for power naps and other common sleep-wake phenomena: a hypothesis
por: George, Peter T.
Publicado: (2017)

Kleine-Levin syndrome: clues to aetiology
por: AlShareef, Saad Mohammed, et al.
Publicado: (2018)

The relationship between obstructive sleep apnea hypopnea syndrome and gastroesophageal reflux disease: a meta-analysis
por: Wu, Zeng-Hong, et al.
Publicado: (2018)

Olfactory function in patients with obstructive sleep apnea and the effect of positive airway pressure treatment: a systematic review and meta-analysis
por: Binar, Murat, et al.
Publicado: (2021)

Obstructive sleep apnea syndrome and risk of renal impairment: a systematic review and meta-analysis with trial sequential analysis
por: Liu, Tongtong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sn4em90altge3i77kobtosnnod