LncRNA 1700020I14Rik promotes AKR1B10 expression and activates Erk pathway to induce hepatocyte damage in alcoholic hepatitis

Alcoholic hepatitis (AH), a kind of alcoholic liver disease, shows poor prognosis. Long noncoding RNAs (lncRNAs) exert critical role in liver diseases. Here, we intended to investigate the possible molecular mechanism that 1700020I14Rik-based regulation of microRNA (miR)-137/Aldo-keto reductase fami...

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Detalles Bibliográficos
Autores principales: Wu, Yue, Qi, Yabin, Bai, Yangqiu, Zhang, Haihui, Zhu, Wenliang, Zhou, Shengli, Zhang, Yanrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418154/
https://www.ncbi.nlm.nih.gov/pubmed/36028503
http://dx.doi.org/10.1038/s41420-022-01135-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418154/
https://www.ncbi.nlm.nih.gov/pubmed/36028503
http://dx.doi.org/10.1038/s41420-022-01135-w

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