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N-glycosylation is crucial for trafficking and stability of SLC3A2 (CD98)

The type II glycoprotein CD98 (SLC3A2) is a membrane protein with pleiotropic roles in cells, ranging from modulation of inflammatory processes, host–pathogen interactions to association with membrane transporters of the SLC7 family. The recent resolution of CD98 structure in complex with LAT1 showe...

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Detalles Bibliográficos
Autores principales: Console, Lara, Scalise, Mariafrancesca, Salerno, Simona, Scanga, Raffaella, Giudice, Deborah, De Bartolo, Loredana, Tonazzi, Annamaria, Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418156/
https://www.ncbi.nlm.nih.gov/pubmed/36028562
http://dx.doi.org/10.1038/s41598-022-18779-4