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Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation
Interleukin-27 is a pleiotropic cytokine whose functions during bacterial infections remain controversial, and its role in patients with S. aureus osteomyelitis is unknown. To address this knowledge gap, we completed a clinical study and observed elevated serum IL-27 levels (20-fold higher, P < 0...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418173/ https://www.ncbi.nlm.nih.gov/pubmed/36028492 http://dx.doi.org/10.1038/s41413-022-00228-7 |