Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in myelodysplastic syndrome

Acquired sideroblastic anemia, characterized by bone marrow ring sideroblasts (RS), is predominantly associated with myelodysplastic syndrome (MDS). Although somatic mutations in splicing factor 3b subunit 1 (SF3B1), which is involved in the RNA splicing machinery, are frequently found in MDS-RS, th...

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Detalles Bibliográficos
Autores principales: Ochi, Tetsuro, Fujiwara, Tohru, Ono, Koya, Suzuki, Chie, Nikaido, Maika, Inoue, Daichi, Kato, Hiroki, Onodera, Koichi, Ichikawa, Satoshi, Fukuhara, Noriko, Onishi, Yasushi, Yokoyama, Hisayuki, Nakamura, Yukio, Harigae, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418223/
https://www.ncbi.nlm.nih.gov/pubmed/36028755
http://dx.doi.org/10.1038/s41598-022-18921-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418223/
https://www.ncbi.nlm.nih.gov/pubmed/36028755
http://dx.doi.org/10.1038/s41598-022-18921-2

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